Furan-2-ylmethanethiol

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Names

[ CAS No. ]:
98-02-2

[ Name ]:
Furan-2-ylmethanethiol

[Synonym ]:
2-Furylmethylsulfide
Furfuryl mercaptan
2-Furanmethanethiol
α-Furfuryl mercaptan
T5OJ B1SH
2-Furfurylmercaptan
EINECS 202-628-2
Furan-2-methanethiol
2-Furylmethyl mercaptan
2-Furylmethanethiol
Furan-2-ylmethanethiol
MFCD00003254
(2-Furanyl)methylmercaptan

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
155.0±0.0 °C at 760 mmHg

[ Molecular Formula ]:
C5H6OS

[ Molecular Weight ]:
114.165

[ Flash Point ]:
45.0±0.0 °C

[ Exact Mass ]:
114.013931

[ PSA ]:
51.94000

[ LogP ]:
1.90

[ Vapour Pressure ]:
4.0±0.2 mmHg at 25°C

[ Index of Refraction ]:
1.524

[ Water Solubility ]:
insoluble

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
LU2100000
CHEMICAL NAME :
2-Furanmethanethiol
CAS REGISTRY NUMBER :
98-02-2
BEILSTEIN REFERENCE NO. :
0383594
LAST UPDATED :
199709
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C5-H6-O-S
MOLECULAR WEIGHT :
114.17
WISWESSER LINE NOTATION :
T5OJ B1SH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
100 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: AD277-689 ** OTHER MULTIPLE DOSE TOXICITY DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
2730 mg/kg/13W-C
TOXIC EFFECTS :
Behavioral - food intake (animal) Nutritional and Gross Metabolic - weight loss or decreased weight gain
REFERENCE :
FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 15,383,1977 ** REPRODUCTIVE DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
1260 mg/kg
SEX/DURATION :
male 42 day(s) pre-mating
TOXIC EFFECTS :
Reproductive - Paternal Effects - testes, epididymis, sperm duct
REFERENCE :
FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 15,383,1977

Safety Information

[ Symbol ]:

GHS02

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H226

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
Xn: Harmful;F: Flammable;

[ Risk Phrases ]:
R10

[ Safety Phrases ]:
S23-S24/25-S16

[ RIDADR ]:
UN 3336 3/PG 3

[ WGK Germany ]:
3

[ RTECS ]:
LU2100000

[ Packaging Group ]:
III

[ Hazard Class ]:
3

[ HS Code ]:
2932999099

Synthetic Route

Precursor & DownStream

Precursor

  • Difurfuryldisulfide
  • Furan
  • 2-methylsulfanyl-1-phenyl-ethanone
  • Furfural
  • 2-(Chloromethyl)furan
  • Furfuryl thioacetate
  • 1-(furan-2-ylmethyl)-2-(methylthio)-4,6-diphenylpyridin-1-ium iodide
  • Furfuryl alcohol
  • (2RS,4R)-furan-2-yl-thiazolidine-4-carboxylic acid

DownStream

  • Ethyl 3-(furfurylthio)propionate
  • Difurfuryldisulfide
  • 2-(2-chloroethylsulfanylmethyl)furan
  • 2-(prop-2-enylsulfanylmethyl)furan
  • 2-((Methyldithio)methyl)furan
  • (Furfurylthio)acetone
  • S-(2-Furylmethyl) propanethioate
  • 2-Furfuryl methyl sulfide
  • Furfuryl thioacetate
  • 3-chloropropyl-2-furfurylsulfide

Customs

[ HS Code ]: 2932190090

[ Summary ]:
2932190090 other compounds containing an unfused furan ring (whether or not hydrogenated) in the structure VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%

Articles

Generation of thiols by biotransformation of cysteine-aldehyde conjugates with baker's yeast.

J. Agric. Food Chem. 51(12) , 3629-35, (2003)

Baker's yeast was shown to catalyze the transformation of cysteine-furfural conjugate into 2-furfurylthiol. The biotransformation's yield and kinetics were influenced by the reaction parameters such a...

Lipase-assisted generation of 2-methyl-3-furanthiol and 2-furfurylthiol from thioacetates.

J. Agric. Food Chem. 50(14) , 4087-90, (2002)

Enzymatic hydrolysis of S-3-(2-methylfuryl) thioacetate and S-2-furfuryl thioacetate using lipase from Candida rugosa produced 2-methyl-3-furanthiol and 2-furfurylthiol, respectively. When reactions w...

Effect of type of oil and addition of delta-tocopherol on model flavor compound stability during storage.

J. Agric. Food Chem. 55(22) , 9189-94, (2007)

The objective of this study was to investigate approaches to protect selected flavor compounds from deterioration when stored in an oil matrix. An aroma compound model mixture was prepared in a medium...


More Articles


Related Compounds

  • Furan-2-yl-methanethiol
  • sodium 2-furylmethanethiolate
  • Furan-2-ylmethanethiol-d2
  • (5-((dimethylamino)Methyl)furan-2-yl)Methanethiol
  • methyl furfuryl thiol
  • (5-pyridin-3-ylfuran-2-yl)methanethiol
  • furan-2-yl-(1-methylimidazol-2-yl)methanone
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • N-(4-fluorophenyl)-4-(6-(3-methyl-1H-pyrazol-1-yl)pyridazin-3-yl)piperazine-1-carboxamide
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • tert-Butyl-DL-alanine
  • 4-amino-N-[2-tert-butyl-1-(tetrahydro-2H-pyran-4-ylmethyl)-1H-benzimidazol-5-yl]-N-ethylbenzenesulfonamide