α-methylstyrene

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Names

[ CAS No. ]:
98-83-9

[ Name ]:
α-methylstyrene

[Synonym ]:
2-Phenyl-2-propene
Prop-1-en-2-ylbenzene
2-methyl-2-phenylethene
α-methyl-styrene
AMS
A-METHYL STYRENE
1-methyl-1-phenyl-ethylene
2-Phenylpropylene
2-Phenylpropene
Benzene, isopropenyl-
Styrene, α-methyl-
UNII-D46R9753IK
β-Phenylpropene
2-phenyl-1-propen
β-Phenylpropylene
1-methyl-1-phenylethene
MFCD00008859
Benzene, (1-methylethenyl)-
α-methyl styrene
Isopropenylbenzene
α-Methylstyrene
EINECS 202-705-0

Chemical & Physical Properties

[ Density]:
0.9±0.1 g/cm3

[ Boiling Point ]:
162.5±7.0 °C at 760 mmHg

[ Melting Point ]:
−24 °C(lit.)

[ Molecular Formula ]:
C₉H₁₀

[ Molecular Weight ]:
118.176

[ Flash Point ]:
45.6±0.0 °C

[ Exact Mass ]:
118.078247

[ LogP ]:
3.25

[ Vapour density ]:
4.1 (vs air)

[ Vapour Pressure ]:
2.8±0.1 mmHg at 25°C

[ Index of Refraction ]:
1.510

[ Water Solubility ]:
insoluble

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: WL5075300

CHEMICAL NAME :: Styrene, alpha-methyl-

CAS REGISTRY NUMBER :: 98-83-9

LAST UPDATED :: 199712

DATA ITEMS CITED :: 40

MOLECULAR FORMULA :: C9-H10

MOLECULAR WEIGHT :: 118.19

WISWESSER LINE NOTATION :: 1YR&U1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration into the eye

SPECIES OBSERVED :: Rodent - rabbit

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Human

DOSE/DURATION :: 600 ppm

TOXIC EFFECTS :: Sense Organs and Special Senses (Olfaction) - effect, not otherwise specified Sense Organs and Special Senses (Eye) - effect, not otherwise specified

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 4900 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LCLo - Lowest published lethal concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 3000 ppm

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 4500 mg/kg

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - cyanosis Nutritional and Gross Metabolic - body temperature decrease

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 16 mL/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LCLo - Lowest published lethal concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - guinea pig

DOSE/DURATION :: 3000 ppm

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 15 gm/kg/30D-I

TOXIC EFFECTS :: Kidney, Ureter, Bladder - proteinuria Blood - changes in leukocyte (WBC) count

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 50 mg/m3/6H/22W-I

TOXIC EFFECTS :: Behavioral - muscle contraction or spasticity Vascular - BP lowering not characterized in autonomic section Nutritional and Gross Metabolic - weight loss or decreased weight gain

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 5 mg/m3/24H/13W-C

TOXIC EFFECTS :: Brain and Coverings - recordings from specific areas of CNS Kidney, Ureter, Bladder - other changes in urine composition Blood - other changes

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 15 gm/kg/30D-I

TOXIC EFFECTS :: Nutritional and Gross Metabolic - weight loss or decreased weight gain

MUTATION DATA

TYPE OF TEST :: Sister chromatid exchange

TEST SYSTEM :: Human Lymphocyte

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 116,379,1983 *** REVIEWS *** ACGIH TLV-STEL 483 mg/m3 (100 ppm) DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: TLV/BEI,1997 ACGIH TLV-TWA 242 mg/m3 (50 ppm) DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: TLV/BEI,1997 *** U.S. STANDARDS AND REGULATIONS *** MSHA STANDARD:air-CL 100 ppm (480 mg/m3) DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: 3,170,1971 OSHA PEL (Gen Indu):CL 100 ppm (480 mg/m3) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1910.1000,1994 OSHA PEL (Construc):CL 100 ppm (480 mg/m3) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1926.55,1994 OSHA PEL (Shipyard):CL 100 ppm (480 mg/m3) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1915.1000,1993 OSHA PEL (Fed Cont):CL 100 ppm (480 mg/m3) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 41,50-204.50,1994 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-AUSTRALIA:TWA 50 ppm (240 mg/m3);STEL 100 ppm (485 mg/m3) JAN 1993 OEL-BELGIUM:TWA 50 ppm (242 mg/m3);STEL 100 ppm (484 mg/m3) JAN 1993 OEL-DENMARK:TWA 50 ppm (240 mg/m3) JAN 1993 OEL-FINLAND:TWA 100 ppm (480 mg/m3);STEL 150 ppm (720 mg/m3) JAN 1993 OEL-FRANCE:TWA 59 ppm (240 mg/m3) JAN 1993 OEL-GERMANY:TWA 100 ppm (480 mg/m3) JAN 1993 OEL-RUSSIA:STEL 5 mg/m3 JAN 1993 OEL-SWITZERLAND:TWA 50 ppm (240 mg/m3) JAN 1993 OEL-THAILAND:TWA 100 ppm (480 mg/m3) JAN 1993 OEL-UNITED KINGDOM:TWA 100 ppm (480 mg/m3);STEL 100 ppm JAN 1993 OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGIH TLV *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH RECOMMENDED EXPOSURE LEVEL (REL) : NIOSH REL TO alpha-METHYLSTYRENE-air:10H TWA 50 ppm;STEL 100 ppm REFERENCE : NIOSH* National Institute for Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda. Volume(issue)/page/year: DHHS #92-100,1992 NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - M1533 No. of Facilities: 1933 (estimated) No. of Industries: 20 No. of Occupations: 32 No. of Employees: 24824 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - M1533 No. of Facilities: 354 (estimated) No. of Industries: 3 No. of Occupations: 4 No. of Employees: 3214 (estimated)

Safety Information

[ Symbol ]:

GHS02, GHS07, GHS09

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H226-H319-H335-H411

[ Precautionary Statements ]:
P273-P305 + P351 + P338-P370 + P378-P391-P403 + P235-P501

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
Xi:Irritant;

[ Risk Phrases ]:
R10;R36/37;R51/53

[ Safety Phrases ]:
S61

[ RIDADR ]:
UN 2303 3/PG 3

[ WGK Germany ]:
2

[ RTECS ]:
WL5075300

[ Packaging Group ]:
III

[ Hazard Class ]:
3

[ HS Code ]:
2902909090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

α-Cumyl alcohol
hyacinth butanal
Cumene
Methyltriphenylphosphonium bromide
Acetophenone
2-methyl-1,2-diphenyl-1-propanone
Benzene,(1E)-1-propen-1-yl-
Diiodomethane
alpha-Bromostyrene

DownStream

Cumene
Tetradecamethyl Cycloheptasiloxane
Decamethylcyclopentasiloxane
Dodecamethylcyclohexasiloxane
1,1,3,3,5,5,7,7,9,9,11,11,13,13-Tetradecamethylheptasiloxane
1,1,3,3,5,5,7,7,9,9,11,11,13,13,15,15-Hexadecamethyloctasilo
1,1,3,3-tetramethyl-1-(2-phenylpropyl)disiloxane
2,2,4,4,6,6,8-heptamethyl-8-(2-phenylpropyl)-1,3,5,7,2,4,6,8-tetraoxatetrasilocane
1-(3-phenylbut-3-enyl)piperidine
(1,1,2,2-TETRAFLUOROETHOXY)BENZENE

Customs

[ HS Code ]: 2902909090

[ Summary ]:
2902909090 other aromatic hydrocarbons。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:2.0%。General tariff:30.0%

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