(S)-(-)-1-Phenylethylamine

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Names

[ CAS No. ]:
98-84-0

[ Name ]:
(S)-(-)-1-Phenylethylamine

[Synonym ]:
(−)-α-Methylbenzylamine
(S)-(−)-1-Phenylethylamine
(S)-(-)-α-Methylbenzylamine
phenyl-1ethylamine
1-Phenylethylamine
Benzenemethanamine, α-methyl-, (αS)-
(1S)-1-Phenylethanamine
S-α-Methylbenzylamine
1-phenyl-ethanamin
S-(-)-α-Phenylethylamine
1-phenyl-ethylamin
1-Fenylethylamin
(S)-1-phenylethylamine
(S)-α-Methylbenzenemethanamine
(S)-α-Phenylethylamine
Benzenemethanamine, α-methyl-, (S)-
(S)-phenylethanamine
S-1-phenylethylamine
EINECS 210-545-8
(-)-α-phenethylamine
(S)-(−)-α-methylbenzylamine
Sumine 2079
MFCD00008069
(S)-(-)-α-phenylethylamine

Chemical & Physical Properties

[ Density]:
1.0±0.1 g/cm3

[ Boiling Point ]:
183.0±9.0 °C at 760 mmHg

[ Melting Point ]:
-65ºC

[ Molecular Formula ]:
C8H11N

[ Molecular Weight ]:
121.180

[ Flash Point ]:
79.4±0.0 °C

[ Exact Mass ]:
121.089149

[ PSA ]:
26.02000

[ LogP ]:
1.44

[ Vapour Pressure ]:
0.8±0.3 mmHg at 25°C

[ Index of Refraction ]:
1.533

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
DP5775000
CHEMICAL NAME :
Benzylamine, alpha-methyl-
CAS REGISTRY NUMBER :
98-84-0
LAST UPDATED :
199806
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C8-H11-N
MOLECULAR WEIGHT :
121.20
WISWESSER LINE NOTATION :
1M1R

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
940 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AMIHBC AMA Archives of Industrial Hygiene and Occupational Medicine. (Chicago, IL) V.2-10, 1950-54. For publisher information, see AEHLAU. Volume(issue)/page/year: 4,119,1951
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
560 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180, Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 6,263,1972
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
240 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180, Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 6,263,1972
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
780 uL/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AMIHBC AMA Archives of Industrial Hygiene and Occupational Medicine. (Chicago, IL) V.2-10, 1950-54. For publisher information, see AEHLAU. Volume(issue)/page/year: 4,119,1951

Safety Information

[ Hazard Codes ]:
C:Corrosive;

[ Risk Phrases ]:
R21/22;R34

[ Safety Phrases ]:
S26-S28-S36/37/39-S45

[ RIDADR ]:
UN 2735 8/PG 2

[ WGK Germany ]:
1

[ Packaging Group ]:
III

Synthetic Route

Precursor & DownStream

Precursor

  • (R)-(+)-1-Phenylethylamine
  • 1-Phenylethanamine
  • Acetophenone

DownStream


Related Compounds

  • (S)-3-(isopropoxycarbonyl-aminomethyl)-5-methyl-hexanoic acid (S)-(-)-1-phenylethylamine salt
  • (S)-PhCH(Me)N=C(Me)Ph
  • (S)-(-)-N-(methyldibenzylidene)-α-methylbenzylamine
  • oxalic acid,N-[(1S)-1-phenylethyl]hydroxylamine
  • 1-Phenylethanamine
  • (S)-1-(4-Bromophenyl)ethanamine
  • Methyl 3-bromo-4-cyano-2-methoxyphenylacetate
  • rac-methyl (1R,2R)-1-cyano-2-(fluorosulfonyl)cyclopropane-1-carboxylate
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 5-Bromo-2-{[1-(6-methoxypyridine-3-carbonyl)piperidin-3-yl]methoxy}pyrimidine
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-(4-(2-((tert-Butoxycarbonyl)amino)ethyl)-1H-1,2,3-triazol-1-yl)acetic acid
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 4-Cyclopropyl-N-[1-(4-fluorophenyl)-2-oxoazetidin-3-yl]-1,3-oxazole-5-carboxamide
  • (1-((((2-Methylpyridin-4-yl)methyl)amino)(phenyl)methyl)cyclopent-3-en-1-yl)methanol
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-