benzal chloride

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Names

[ CAS No. ]:
98-87-3

[ Name ]:
benzal chloride

[Synonym ]:
chlorobenza
phenyldichloromethane
benzal
dichloromethylbenzene
bis-chloromethylbenzene
Benaylbichloride
Benzyl dichoride
MFCD00000829
4-bis-chloro-methylbenzene
benzylidene chloride
Chlorkbenzal
1,1-dichlorotoluene
Chlorobenzal
EINECS 202-709-2
Benzalchlorid

Chemical & Physical Properties

[ Density]:
1.254

[ Boiling Point ]:
207 °C

[ Melting Point ]:
-16 °C

[ Molecular Formula ]:
C7H6Cl2

[ Molecular Weight ]:
161.02900

[ Flash Point ]:
92°C

[ Exact Mass ]:
159.98500

[ LogP ]:
3.16280

[ Index of Refraction ]:
1.5500

[ Stability ]:
Stable, but moisture sensitive. Combustible. Incompatible with strong bases, strong oxidizing agents, most metals. Readily hydrolyzes in acidic or basic conditions.

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
CZ5075000
CHEMICAL NAME :
Benzene, (dichloromethyl)-
CAS REGISTRY NUMBER :
98-87-3
BEILSTEIN REFERENCE NO. :
1099407
LAST UPDATED :
199710
DATA ITEMS CITED :
21
MOLECULAR FORMULA :
C7-H6-Cl2
MOLECULAR WEIGHT :
161.03
WISWESSER LINE NOTATION :
GYGR

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
3249 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
61 ppm/2H
TOXIC EFFECTS :
Brain and Coverings - recordings from specific areas of CNS Behavioral - excitement Lungs, Thorax, or Respiration - respiratory depression
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
2462 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
32 ppm/2H
TOXIC EFFECTS :
Brain and Coverings - recordings from specific areas of CNS Behavioral - excitement Lungs, Thorax, or Respiration - respiratory depression
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Mammal - species unspecified
DOSE/DURATION :
1400 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Mammal - species unspecified
DOSE/DURATION :
210 mg/m3
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
9200 mg/kg/50W-I
TOXIC EFFECTS :
Tumorigenic - Carcinogenic by RTECS criteria Lungs, Thorax, or Respiration - tumors Skin and Appendages - tumors
TYPE OF TEST :
TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
35200 mg/kg/42W-I
TOXIC EFFECTS :
Tumorigenic - neoplastic by RTECS criteria Lungs, Thorax, or Respiration - tumors Skin and Appendages - tumors

MUTATION DATA

TYPE OF TEST :
DNA repair
TEST SYSTEM :
Bacteria - Bacillus subtilis
DOSE/DURATION :
31 umol/disc
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 58,143,1978 *** REVIEWS *** IARC Cancer Review:Animal Limited Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 29,65,1982 IARC Cancer Review:Human Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 29,65,1982 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-FINLAND;Carcinogen JAN 1993 OEL-GERMANY;Carcinogen JAN 1993 OEL-RUSSIA:STEL 0.5 mg/m3 JAN 1993 OEL-SWEDEN;Carcinogen JAN 1993

Safety Information

[ Symbol ]:

GHS05, GHS06, GHS08

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H302-H315-H318-H331-H335-H351

[ Precautionary Statements ]:
P261-P280-P305 + P351 + P338-P311

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
T

[ Risk Phrases ]:
22-23-37/38-40-41

[ Safety Phrases ]:
S23-S26-S36/37/39-S45-S38-S36/37

[ RIDADR ]:
1886

[ RTECS ]:
CZ5075000

[ Packaging Group ]:
II

[ Hazard Class ]:
6.1

[ HS Code ]:
2903999090

Synthetic Route

Precursor & DownStream

Precursor

  • Benzaldehyde
  • Benzotrichloride
  • Benzyl chloride
  • Oxalyl chloride
  • Acetophenone
  • 3-Methyl-2-butanone
  • Valeraldehyde
  • Cyclopentanone
  • 3-Pentanone
  • 3-chloro-3-(phenyl)diaziridine

DownStream

  • Chloromethane
  • 2-[chloro(propan-2-yl)phosphoryl]propane
  • Benzaldehyde
  • diisopropylphosphinic anhydride
  • N-(2-Naphthyl)-2-naphthalenamine
  • Phenylacetic acid
  • Benzeneacetic acid, α-chloro-
  • Phenylmalonic acid
  • Fenipentol
  • (DIFLUOROMETHYL)BENZENE

Customs

[ HS Code ]: 2903999090

[ Summary ]:
2903999090 halogenated derivatives of aromatic hydrocarbons VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%

Articles

Carcinogenicity of benzyl chloride, benzal chloride, benzotrichloride and benzoyl chloride in mice by skin application.

Gann 72(5) , 655-64, (1981)

The carcinogenicity of benzyl chloride (BYC), benzal chloride (BAC), benzotrichloride (BTC) and benzoyl chloride (BOC), which were suspected as causative agents of lung cancer and maxillary malignant ...

Lung cancer mortality among workers in a factory manufacturing chlorinated toluenes: 1961-84.

Br. J. Ind. Med. 46(6) , 425-7, (1989)

FTIR and FT Raman spectra, vibrational assignments, ab initio, DFT and normal coordinate analysis of alpha,alpha dichlorotoluene.

Spectrochim. Acta. A. Mol. Biomol. Spectrosc. 73(2) , 277-80, (2009)

The vibrational spectra of alpha,alpha dichlorotoluene have been recorded using PerkinElmer 521 spectrometer in the range 3600-100 cm(-1). A detailed vibrational spectral analysis has been carried out...


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Related Compounds

  • o-nitrobenzal chloride
  • 2-fluorobenzal chloride
  • 4-ethyl benzal chloride
  • 2,4-DICHLORO BENZAL CHLORIDE
  • 2,4-Dichloro benzal chloride
  • trifluoromethyl benzal chloride
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • 3-(benzenesulfonyl)-6-methoxy-N-phenylquinolin-4-amine
  • N-(3,4-difluorophenyl)-1-(7H-purin-6-yl)-4-piperidinecarboxamide
  • tert-Butyl-DL-alanine