boc-achpa

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Names

[ CAS No. ]:
98105-45-4

[ Name ]:
boc-achpa

[Synonym ]:
BOC-CYCLOHEXYLSTATINE
N-Boc-cyclohexyl statine
N-Boc-(3S,4S)-4-amino-5-cyclohexyl-3-hydroxypentanoic acid
boc-(3s,4s)-4-amino-5-cyclohexyl-3-hydroxypentanoic acid
boc-5-cyclohexylstatine
BOC-(3S,4S)-4-AMINO-3-HYDROXY-5-CYCLOHEXYL-PENTANOIC ACID
N-tert-butoxycarbonyl-(3S,4S)-4-amino-5-cyclohexyl-3-hydroxypentanoic acid
(3S,4S)-4-(N-tert-butoxycarbonyl)amino-5-cyclohexyl-3-hydroxypentanoic acid
N-T-BOC-5-CYCLOHEXYLSTATINE
N-(tert-butoxycarbonyl)-5-cyclohexylstatine
(3S,4S)-4-(t-Boc-amino)-5-cyclohexyl-3-hydroxypentanoic acid
N-(t-butoxycarbonyl)-(3S,4S)-4-amino-5-cyclohexyl-3-hydroxypentanoic acid
BOC-CHA-STATINE
N-Boc-4(S)-amino-5-cyclohexyl-3(S)-hydroxy-pentanoic acid
BOC-(S,S)-4-AMINO-3-HYDROXY-5-CYCLOHEXYL PENTANOIC ACID

Chemical & Physical Properties

[ Density]:
1.121 g/cm3

[ Boiling Point ]:
498.1ºC at 760 mmHg

[ Molecular Formula ]:
C16H29NO5

[ Molecular Weight ]:
315.40500

[ Flash Point ]:
255ºC

[ Exact Mass ]:
315.20500

[ PSA ]:
95.86000

[ LogP ]:
3.07660

[ Index of Refraction ]:
1.497

MSDS

Click to get detail MSDS

Safety Information

[ RIDADR ]:
NONH for all modes of transport

[ HS Code ]:
2924299090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Fmoc-(3S,4S)-AHPPA-OH
  • Boc-L-phenylalanine
  • Boc-L-phenylalanine methyl ester
  • Carbamic acid, N-[(1S)-2-cyclohexyl-1-formylethyl]-, 1,1-dimethylethyl ester
  • (3S,4S)-3,4-DIAZIDO-1-(PHENYLMETHYL)PYRROLIDINE
  • N-Boc-β-keto-γ-phenylalanine
  • Boc-Cha-OMe

DownStream

  • 5-cyclohexyl-3-hydroxy-N-(2-morpholin-4-ylethyl)-4-[[2-[[4-morpholin-4-yl-2-(naphthalen-1-ylmethyl)-4-oxobutanoyl]amino]-3-(1,3-thiazol-4-yl)propanoyl]amino]pentanamide

Customs

[ HS Code ]: 2924299090

[ Summary ]:
2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Articles

Renin inhibitors. Syntheses of subnanomolar, competitive, transition-state analogue inhibitors containing a novel analogue of statine.

J. Med. Chem. 28(12) , 1779-90, (1985)

Analogues of the renin octapeptide substrate were synthesized in which replacement of the scissile dipeptide with (3S,4S)-4-amino-3-hydroxy-6-methylheptanoic acid (statine, Sta) transformed the substr...


More Articles

Related Compounds

  • Boc-PheΨ[CHOHCH=CHCONH]ACHPA-Leu-NHCH2-m-Ph-CH2NHZ
  • Boc-Ser(Fmoc-Thr(tBu))-OH
  • Boc-(R)-3-Amino-4-(2-naphthyl)-butyric acid
  • Boc-(R)-3-amino-4-(2-methylphenyl)-butyric acid
  • boc-trp-met-asp-phe-nh2
  • Boc-(R)-3-Amino-(6-phenyl)-5-hexenoic acid
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 1-(But-3-yn-2-yl)-4-(difluoromethoxy)benzene
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • tert-Butyl-DL-alanine
  • 6-Acetamidopyrimidine-4-carboxylic acid