Drotaverine hydrochloride

Suppliers

Names

[ CAS No. ]:
985-12-6

[ Name ]:
Drotaverine hydrochloride

[Synonym ]:
6,7,3',4'-Tetraethoxy-1-benzal-1,2,3,4-tetrahydroisoquinoline hydrochloride
DROTAVERINE HCL
DROTAVERINE HYDROCHLORIDE
Drotaverine HCl ;1-[(3,4-Diethoxyphenyl)methylene]-6,7-diethoxy 1,2,3,4-tetrahydroisoquinoline HCL
Drotaverinium chloride
Isodihydroperparine hydrochloride
MFCD01754602
Drotaverin hydrochloride
Isoquinoline, 1-[(3,4-diethoxyphenyl)methylene]-6,7-diethoxy-1,2,3,4-tetrahydro-, (1Z)-, hydrochloride (1:1)
(1Z)-1-(3,4-Diethoxybenzylidene)-6,7-diethoxy-1,2,3,4-tetrahydroisoquinoline hydrochloride
(1Z)-1-[(3,4-Diethoxyphenyl)methyliden]-6,7-diethoxy-1,2,3,4-tetrahydroisochinolinhydrochlorid
Tetraspasmin-Lefa
(1Z)-1-(3,4-Diethoxybenzylidene)-6,7-diethoxy-1,2,3,4-tetrahydroisoquinoline hydrochloride (1:1)
No-Spa hydrochloride

Chemical & Physical Properties

[ Density]:
1.097 g/cm3

[ Boiling Point ]:
564ºC at 760 mmHg

[ Melting Point ]:
208-212ºC

[ Molecular Formula ]:
C24H32ClNO4

[ Molecular Weight ]:
433.968

[ Flash Point ]:
240.7ºC

[ Exact Mass ]:
433.201996

[ PSA ]:
48.95000

[ LogP ]:
6.05600

[ Storage condition ]:
-20°C Freezer

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
NX5014000
CHEMICAL NAME :
Isoquinoline, 1,2,3,4-tetrahydro-6,7-diethoxy-1-((3,4-diethoxypheny l)methylene)-, hydrochloride
CAS REGISTRY NUMBER :
985-12-6
LAST UPDATED :
199606
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C24-H31-N-O4.Cl-H
MOLECULAR WEIGHT :
434.02

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
540 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
USXXAM United States Patent Document. (U.S. Patent Office, Box 9, Washington, DC 20231) Volume(issue)/page/year: #4035366
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
14600 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
USXXAM United States Patent Document. (U.S. Patent Office, Box 9, Washington, DC 20231) Volume(issue)/page/year: #4035366
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
350 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
USXXAM United States Patent Document. (U.S. Patent Office, Box 9, Washington, DC 20231) Volume(issue)/page/year: #4035366
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
15 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
USXXAM United States Patent Document. (U.S. Patent Office, Box 9, Washington, DC 20231) Volume(issue)/page/year: #4035366

Safety Information

[ HS Code ]:
2933990090

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Related Compounds

  • Drotaverin hydrochloride
  • Tyrocidine, hydrochloride
  • Triprolidine hydrochloride
  • Minoxidil hydrochloride
  • Elacridar hydrochloride
  • dodecylamine hydrochloride
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-(2-Fluorophenyl)-1-(4-hydroxypiperidin-1-yl)ethan-1-one
  • 6-chloro-3-[(2E)-3-(4-ethoxy-3-methoxyphenyl)prop-2-enoyl]-2H-chromen-2-one
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1-methyl-3-(pentan-3-yl)-1H-pyrazol-5-amine
  • N-[(1-methanesulfonylpiperidin-4-yl)methyl]-2,5-dimethylfuran-3-carboxamide
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • N-{3-[(2,5-dimethoxyphenyl)amino]-3-oxopropyl}-1,3,4,9-tetrahydro-2H-beta-carboline-2-carboxamide
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol