Methyl 3-nitro-4-hydroxybenzoate

Suppliers

Names

[ CAS No. ]:
99-42-3

[ Name ]:
Methyl 3-nitro-4-hydroxybenzoate

[Synonym ]:
methyl 4-hydroxy-3-nitrobenzoate
MFCD00014695
EINECS 202-755-3

Chemical & Physical Properties

[ Density]:
1.432 g/cm3

[ Boiling Point ]:
311.1ºC at 760 mmHg

[ Melting Point ]:
74-76°C

[ Molecular Formula ]:
C8H7NO5

[ Molecular Weight ]:
197.14500

[ Flash Point ]:
141.9ºC

[ Exact Mass ]:
197.03200

[ PSA ]:
92.35000

[ LogP ]:
1.61020

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
DH2528400
CHEMICAL NAME :
Benzoic acid, 4-hydroxy-3-nitro-, methyl ester
CAS REGISTRY NUMBER :
99-42-3
BEILSTEIN REFERENCE NO. :
2115197
LAST UPDATED :
199710
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C8-H7-N-O5

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
2500 mg/kg
TOXIC EFFECTS :
Gastrointestinal - ulceration or bleeding from stomach
REFERENCE :
EPASR* United States Environmental Protection Agency, Office of Pesticides and Toxic Substances. (U.S. Environmental Protection Agency, 401 M St., SW, Washington, DC 20460) History unknown. Volume(issue)/page/year: 8EHQ-0287-0657S
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>2 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
EPASR* United States Environmental Protection Agency, Office of Pesticides and Toxic Substances. (U.S. Environmental Protection Agency, 401 M St., SW, Washington, DC 20460) History unknown. Volume(issue)/page/year: 8EHQ-0287-0657S

Safety Information

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36/37/39

[ RTECS ]:
DH2528400

[ HS Code ]:
2918290000

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Methanol
  • 4-Hydroxy-3-nitrobenzoic acid
  • SodiuM bicarbonate
  • Methyl 4-hydroxybenzoate
  • Sulfuric acid
  • Trimethyloxonium tetrafluoroborate
  • dichloroethane

DownStream

  • methyl 3-bromo-4-hydroxy-5-nitrobenzoate
  • Methyl 3-amino-5-bromo-4-hydroxybenzoate
  • Methyl 3,4-dihydro-2H-benzo[1,4]oxazine-6-carboxylate
  • Orthocaine
  • METHYL 2-METHYLBENZO[D]OXAZOLE-5-CARBOXYLATE
  • 3-Amino-4-hydroxybenzoic acid
  • METHYL 3-OXO-3,4-DIHYDRO-2H-BENZO[B][1,4]OXAZINE-6-CARBOXYLATE
  • Benzamide, 3-amino-4-hydroxy- (9CI)
  • 4-hydroxy-3-nitrobenzamide
  • methyl 3-nitro-4-[2-(2-nitrophenoxy)ethoxy]benzoate

Customs

[ HS Code ]: 2918290000

[ Summary ]:
HS: 2918290000 other carboxylic acids with phenol function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) VAT:17.0% MFN tariff:6.5% General tariff:30.0%

Related Compounds

  • Methyl-[3-nitro-4-dimethylamino-phenyl]-sulfon
  • METHYL 3-NITRO-4-PIPERAZINOBENZENECARBOXYLATE
  • methyl 3-nitro-4-[2-(2-nitrophenoxy)ethoxy]benzoate
  • methyl 3-nitro-4-bromomethylbenzoate
  • methyl 3-nitro-4-(propylamino)benzoate
  • Methyl 3-nitro-4-(piperazin-1-yl)benzoate
  • N-(2-(furan-2-yl)-2-thiomorpholinoethyl)thiophene-3-carboxamide
  • N-(2-(furan-2-yl)-2-thiomorpholinoethyl)-2-methylbenzamide
  • Methyl 2-(2-((tert-butoxycarbonyl)amino)ethoxy)-4-chloro-6-fluorobenzoate
  • N-(2-(furan-2-yl)-2-thiomorpholinoethyl)-4-methylthiophene-2-carboxamide
  • N-(2-(furan-2-yl)-2-thiomorpholinoethyl)-4-methyl-1,2,3-thiadiazole-5-carboxamide
  • N-(2-(furan-2-yl)-2-thiomorpholinoethyl)-2-(m-tolyl)acetamide
  • N-(2-(furan-2-yl)-2-thiomorpholinoethyl)-4-methoxybenzamide
  • N-(2-(furan-2-yl)-2-thiomorpholinoethyl)-2-phenoxyacetamide
  • N-(2-(furan-2-yl)-2-thiomorpholinoethyl)-1-methyl-2-oxo-1,2-dihydropyridine-3-carboxamide
  • 2-(4-fluorophenyl)-N-(2-(furan-2-yl)-2-thiomorpholinoethyl)acetamide
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.