Oxybuprocaine
Names
[ CAS No. ]:
99-43-4
[ Name ]:
Oxybuprocaine
[Synonym ]:
Benoxinate
Oxybuprocaine
Oxybucaine
Prescaina
Oxibuprocainum
Conjucain
2-(Diethylamino)ethyl 4-amino-3-butoxybenzoate
4-Amino-3-butoxy-benzoesaeure-(2-diaethylamino-aethylester)
4-amino-3-butoxy-benzoic acid-(2-diethylamino-ethyl ester)
Benoxil
Oxibuprocaina
Oxibuprokain
Oxyriprocaine
Chemical & Physical Properties
[ Density]:
1.052g/cm3
[ Boiling Point ]:
446.9ºC at 760mmHg
[ Molecular Formula ]:
C17H28N2O3
[ Molecular Weight ]:
308.41600
[ Flash Point ]:
224.1ºC
[ Exact Mass ]:
308.21000
[ PSA ]:
64.79000
[ LogP ]:
3.52750
[ Index of Refraction ]:
1.524
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- DG1502000
- CHEMICAL NAME :
- Benzoic acid, 4-amino-3-butoxy-, 2-(diethylamino)ethyl ester
- CAS REGISTRY NUMBER :
- 99-43-4
- BEILSTEIN REFERENCE NO. :
- 2288926
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 4
- MOLECULAR FORMULA :
- C17-H28-N2-O3
- MOLECULAR WEIGHT :
- 308.47
- WISWESSER LINE NOTATION :
- 4OR BZ EVO2N2&2
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 37 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- AACRAT Anesthesia and Analgesia (New York). (Elsevier Science Pub. Co., Inc., 52 Vanderbilt Ave., New York, NY 10017) V.36- 1957- Volume(issue)/page/year: 38,265,1959
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 75 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- AACRAT Anesthesia and Analgesia (New York). (Elsevier Science Pub. Co., Inc., 52 Vanderbilt Ave., New York, NY 10017) V.36- 1957- Volume(issue)/page/year: 38,265,1959
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 7800 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 3,612,1953
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Bird - quail
- DOSE/DURATION :
- 100 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- EESADV Ecotoxicology and Environmental Safety. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1977- Volume(issue)/page/year: 6,149,1982
Safety Information
[ HS Code ]:
2922509090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2922509090
[ Summary ]:
2922509090. other amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%