Nebivolol

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Names

[ CAS No. ]:
99200-09-6

[ Name ]:
Nebivolol

[Synonym ]:
Nebivolol
MFCD00865796
(S,R,R,R)-NEBIVOLOL-D2,15N HYDROCHLORIDE
Nibivolol
rac-nebivolol
NEBIVOLOLHCL
NEBIVOLOL HYDROCHLORIDE
NEBIVOLOL-D4

Chemical & Physical Properties

[ Density]:
1.309 g/cm3

[ Boiling Point ]:
600.5ºC at 760 mmHg

[ Melting Point ]:
155-156°C(lit.)

[ Molecular Formula ]:
C22H25F2NO4

[ Molecular Weight ]:
405.43500

[ Flash Point ]:
316.9ºC

[ Exact Mass ]:
405.17500

[ PSA ]:
70.95000

[ LogP ]:
2.75450

[ Index of Refraction ]:
1.58

[ Storage condition ]:
20°C

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • N-[(S,S)-1-hydroxy-2-(6-fluoro-chroman-4-one-2-yl)]-N-[(R,S)-1-hydroxy-2-(6-fiuoro-chroman-4-one-2-yl)]-amine
  • N-benzyl-N-[(R,R)-1-hydroxy-2-(6-fluoro-chroman-4-one-2-yl)]-N-[(S,R)-1-hydroxy-2-(6-fluoro-chroman-4-one-2-yl)]-amine
  • 6-Fluoro-3,4-dihydro-2-oxiranyl-2H-1-benzopyran
  • Dibenzylamine
  • Benzylamine

DownStream

  • nebivolol

Related Compounds

  • Nebivolol
  • Nebivolol
  • nebivolol
  • l-nebivolol
  • l-nebivolol
  • NEBIVOLOL-D4
  • 7-bromo-3,4-dihydro-2H-1,2,4-benzothiadiazine-1,1-dione
  • 4-Fluoro-3-(thiomorpholinomethyl)benzonitrile
  • N,N-dimethyl-N'-(5-chloro-2-nitrophenyl)benzene-1,4-diamine
  • N-(1-acetylindolin-6-yl)-1-(2-chlorophenyl)methanesulfonamide
  • 3-(6-Chloro-pyrazin-2-yloxymethyl)-benzonitrile
  • 2-(Thiomorpholinomethyl)benzonitrile
  • 3-[(6-Chloro-pyrazin-2-ylamino)-methyl]-benzonitrile
  • 2-[(4-Methyl-2-thiazolyl)methoxy]-6-(1-piperazinyl)pyrazine
  • 5-Bromo-3-(3-chloro-benzyloxy)-pyrazin-2-ylamine
  • 3-[(3-Chlorophenyl)methoxy]-5-(1-piperazinyl)-2-pyrazinamine