5-bromo-3-hydroxy-3-(pyridin-2-ylmethyl)-1H-indol-2-one

Names

[ CAS No. ]:
99304-31-1

[ Name ]:
5-bromo-3-hydroxy-3-(pyridin-2-ylmethyl)-1H-indol-2-one

Chemical & Physical Properties

[ Density]:
1.643g/cm3

[ Boiling Point ]:
525.5ºC at 760 mmHg

[ Molecular Formula ]:
C14H11BrN2O2

[ Molecular Weight ]:
319.15300

[ Flash Point ]:
271.6ºC

[ Exact Mass ]:
318.00000

[ PSA ]:
65.71000

[ LogP ]:
2.31160

[ Index of Refraction ]:
1.684

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
NM3257500
CHEMICAL NAME :
2H-Indol-2-one, 1,3-dihydro-5-bromo-3-hydroxy-3-(2-pyridinylmethyl)-
CAS REGISTRY NUMBER :
99304-31-1
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C14-H11-Br-N2-O2
MOLECULAR WEIGHT :
319.18
WISWESSER LINE NOTATION :
T56 BMV DHJ DQ D1- BT6NTJ& GE

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
700 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PCJOAU Pharmaceutical Chemistry Journal (English Translation). Translation of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No.1- 1967- Volume(issue)/page/year: 19,562,1985

Synthetic Route

Click to get detail synthetic route

Related Compounds

  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 2-(Cyclopropylmethyl)-6-ethylthieno[2,3-d]pyrimidine-4-carboxylic acid
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • tert-Butyl-DL-alanine
  • 4-amino-N-[2-tert-butyl-1-(tetrahydro-2H-pyran-4-ylmethyl)-1H-benzimidazol-5-yl]-N-ethylbenzenesulfonamide