3-N-Boc-aminopyrrolidine

Names

[ CAS No. ]:
99724-19-3

[ Name ]:
3-N-Boc-aminopyrrolidine

[Synonym ]:
tert-Butyl pyrrolidin-3-ylcarbamate
MFCD00059040

Chemical & Physical Properties

[ Density]:
1.0±0.1 g/cm3

[ Boiling Point ]:
286.4±29.0 °C at 760 mmHg

[ Melting Point ]:
67ºC

[ Molecular Formula ]:
C₉H₁₈N₂O₂

[ Molecular Weight ]:
186.251

[ Flash Point ]:
127.0±24.3 °C

[ Exact Mass ]:
186.136826

[ PSA ]:
50.36000

[ LogP ]:
0.93

[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C

[ Index of Refraction ]:
1.480

[ Storage condition ]:
2-8°C

MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
36/37/38

[ Safety Phrases ]:
26

[ RIDADR ]:
NONH for all modes of transport

[ HS Code ]:
2933990090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

(R)-1-Benzyl-3-(Boc-Amino)pyrrolidine
Di-tert-butyl dicarbonate
3-Pyrrolidinamine

DownStream

8-chloro-1-cyclopropyl-6-fluoro-7-[3-[(2-methylpropan-2-yl)oxycarbonylamino]pyrrolidin-1-yl]-4-oxoquinoline-3-carboxylic acid
[1-(4-AMINO-PHENYL)-PYRROLIDIN-3-YL]-CARBAMIC ACID TERT-BUTYL ESTER
TERT-BUTYL (1-METHYLPYRROLIDIN-3-YL)CARBAMATE
tert-butyl N-(1-propan-2-ylpyrrolidin-3-yl)carbamate

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

A novel approach for LC-MS/MS-based chiral metabolomics fingerprinting and chiral metabolomics extraction using a pair of enantiomers of chiral derivatization reagents.

Anal. Chim. Acta 898 , 73-84, (2015)

Chiral metabolites are found in a wide variety of living organisms and some of them are understood to be physiologically active compounds and biomarkers. However, the overall analysis of chiral metabo...

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