VGSCs-IN-1 structure
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Common Name | VGSCs-IN-1 | ||
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CAS Number | 1204296-79-6 | Molecular Weight | 303.30 | |
Density | N/A | Boiling Point | N/A | |
Molecular Formula | C12H12F3N3OS | Melting Point | N/A | |
MSDS | N/A | Flash Point | N/A |
Use of VGSCs-IN-1VGSCs-IN-1 (compound 14), a 2-piperazine analog of Riluzole (HY-B0211), is a human voltage-gated sodium channels (VGSCs) inhibitor. VGSCs-IN-1 shows great Nav1.4 blocking activity. VGSCs-IN-1 has a pKa of 7.6 and a cLog P of 2.4. VGSCs-IN-1 can be used for cell excitability disorders research[1]. |
Name | 2-(piperazin-1-yl)-6-(trifluoromethoxy)benzothiazole |
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Description | VGSCs-IN-1 (compound 14), a 2-piperazine analog of Riluzole (HY-B0211), is a human voltage-gated sodium channels (VGSCs) inhibitor. VGSCs-IN-1 shows great Nav1.4 blocking activity. VGSCs-IN-1 has a pKa of 7.6 and a cLog P of 2.4. VGSCs-IN-1 can be used for cell excitability disorders research[1]. |
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Related Catalog | |
Target |
hNav1.4 hNav1.7 |
References |
Molecular Formula | C12H12F3N3OS |
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Molecular Weight | 303.30 |
Exact Mass | 303.06500 |
PSA | 65.63000 |
LogP | 2.99830 |