Fumonisin B1-13C34
Modify Date: 2024-01-11 13:47:20
Fumonisin B1-13C34 structure
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Common Name | Fumonisin B1-13C34 | ||
|---|---|---|---|---|
| CAS Number | 1217458-62-2 | Molecular Weight | N/A | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | 13C34H59NO15 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 2 °C | |
| Symbol |
GHS02, GHS07 |
Signal Word | Danger | |
Use of Fumonisin B1-13C34Fumonisin B1-13C34 is the 13C labeled Fumonisin B1 (HY-N6719)[1]. Fumonisin B1 is a mycotoxin produced from Fusarium moniliforme. Fumonisin B1 is a potent inhibitor of sphingosine N-acyltransferase (ceramide synthase) and disrupts de novo sphingolipid biosynthesis. Fumonisin B1 is the most abundant and toxic fumonisin[2][3]. |
| Name | Fumonisin B1-13C34 solution |
|---|---|
| Synonym | More Synonyms |
| Description | Fumonisin B1-13C34 is the 13C labeled Fumonisin B1 (HY-N6719)[1]. Fumonisin B1 is a mycotoxin produced from Fusarium moniliforme. Fumonisin B1 is a potent inhibitor of sphingosine N-acyltransferase (ceramide synthase) and disrupts de novo sphingolipid biosynthesis. Fumonisin B1 is the most abundant and toxic fumonisin[2][3]. |
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| Related Catalog | |
| Target |
Sphingosine N-acyltransferase[2] |
| In Vitro | 氢、碳和其他元素的稳定重同位素已被纳入药物分子中，主要作为药物开发过程中定量的示踪剂。氘化引起了人们的关注，因为它可能影响药物的药代动力学和代谢谱[1]。 Fumonisin B1 改变猴肾细胞基因表达和信号转导通路[2]。 Fumonisin B1 增加鞘脂代谢的初始破坏和鞘氨醇在 LLC-PK1 肾细胞中的积累，导致大鼠星形胶质细胞凋亡型 DNA 损伤[2]。 |
| References |
| Molecular Formula | 13C34H59NO15 |
|---|---|
| Flash Point | 2 °C |
| Storage condition | −20°C |
| Symbol |
GHS02, GHS07 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H225-H302 + H312 + H332-H319 |
| Precautionary Statements | P210-P280-P305 + P351 + P338 |
| Hazard Codes | F,Xn |
| Risk Phrases | 11-20/21/22-36 |
| Safety Phrases | 26-36/37-16 |
| RIDADR | UN 1648 3/PG 2 |
| EINECS 808-555-8 |