4,6-Bis[(2H3)methyloxy]-2-pyrimidinamine

Modify Date: 2023-01-27 01:40:58

4,6-Bis[(2H3)methyloxy]-2-pyrimidinamine Structure
4,6-Bis[(2H3)methyloxy]-2-pyrimidinamine structure
Common Name 4,6-Bis[(2H3)methyloxy]-2-pyrimidinamine
CAS Number 1219803-92-5 Molecular Weight 161.191
Density 1.2±0.1 g/cm3 Boiling Point 356.4±45.0 °C at 760 mmHg
Molecular Formula C6H3D6N3O2 Melting Point N/A
MSDS N/A Flash Point 169.4±28.7 °C

 Use of 4,6-Bis[(2H3)methyloxy]-2-pyrimidinamine


2-Amino-4,6-dimethoxy-pyrimidine-d6 is the deuterium labeled 2-Amino-4,6-dimethoxypyrimidine[1].

 Names

Name 4,6-bis(trideuteriomethoxy)pyrimidin-2-amine
Synonym More Synonyms

 4,6-Bis[(2H3)methyloxy]-2-pyrimidinamine Biological Activity

Description 2-Amino-4,6-dimethoxy-pyrimidine-d6 is the deuterium labeled 2-Amino-4,6-dimethoxypyrimidine[1].
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 356.4±45.0 °C at 760 mmHg
Molecular Formula C6H3D6N3O2
Molecular Weight 161.191
Flash Point 169.4±28.7 °C
Exact Mass 161.107132
PSA 70.99000
LogP 1.30
Vapour Pressure 0.0±0.8 mmHg at 25°C
Index of Refraction 1.547
Storage condition 2-8°C

 Synonyms

2-Amino-4,6-dimethoxypyrimidine-d6
4,6-Bis[(H)methyloxy]pyrimidin-2-amine
4,6-Dimethoxy-2-aminopyrimidine-d6
2-Pyrimidinamine, 4,6-bis(methyl-d-oxy)-
4,6-Bis[(H)methyloxy]-2-pyrimidinamine
4,6-Dimethoxy-2-pyrimidinamine-d6
2-AMINO-4,6-DIMETHOXYPYRIMIDINE-D6,OFF-WHITE