Topoisomerase I inhibitor 9

Modify Date: 2024-01-29 10:37:17

Topoisomerase I inhibitor 9 Structure
Topoisomerase I inhibitor 9 structure
Common Name Topoisomerase I inhibitor 9
CAS Number 1228150-86-4 Molecular Weight 498.19
Density N/A Boiling Point N/A
Molecular Formula C23H15Br2FN2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Topoisomerase I inhibitor 9


Topoisomerase I inhibitor 9 (compound 3d) is a leishmanial topoisomerase IB inhibitor. Topoisomerase I inhibitor 9 has antileishmanial activity against L. donovani promastigotes, with the IC50 of 34.81μM[1].

 Names

Name Topoisomerase I inhibitor 9

 Topoisomerase I inhibitor 9 Biological Activity

Description Topoisomerase I inhibitor 9 (compound 3d) is a leishmanial topoisomerase IB inhibitor. Topoisomerase I inhibitor 9 has antileishmanial activity against L. donovani promastigotes, with the IC50 of 34.81μM[1].
Related Catalog
Target

34.81 μM[1]

References

[1]. Kour P, et al. Design, synthesis, and biological evaluation of 3,3'-diindolylmethane N-linked glycoconjugate as a leishmanial topoisomerase IB inhibitor with reduced cytotoxicity. RSC Med Chem. 2023;14(10):2100-2114. Published 2023 Aug 30.  

 Chemical & Physical Properties

Molecular Formula C23H15Br2FN2
Molecular Weight 498.19
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