Cyclooctyne-O-amido-PEG4-NHS ester

Modify Date: 2024-01-09 10:55:44

Cyclooctyne-O-amido-PEG4-NHS ester structure	Common Name	Cyclooctyne-O-amido-PEG4-NHS ester
	CAS Number	2101206-50-0	Molecular Weight	526.58
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₅H₃₈N₂O₁₀	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Cyclooctyne-O-amido-PEG4-NHS ester

Cyclooctyne-O-amido-PEG4-NHS ester is a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

Name	Cyclooctyne-O-amido-PEG4-NHS ester

Description	Cyclooctyne-O-amido-PEG4-NHS ester is a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker
Target	Non-cleavable
In Vitro	ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].
References	[1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.

Molecular Formula	C₂₅H₃₈N₂O₁₀
Molecular Weight	526.58