Zelminemab

Modify Date: 2024-01-10 20:09:36

Zelminemab Structure
Zelminemab structure
Common Name Zelminemab
CAS Number 2225850-33-7 Molecular Weight N/A
Density N/A Boiling Point N/A
Molecular Formula N/A Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Zelminemab


Zelminemab (AMG-301) is a human monoclonal antibody that inhibits PACAP type I (PAC1) receptor[1].

 Names

Name Zelminemab

 Zelminemab Biological Activity

Description Zelminemab (AMG-301) is a human monoclonal antibody that inhibits PACAP type I (PAC1) receptor[1].
Related Catalog
In Vivo Zelminemab(10 mg/kg;i.v.;一次)降低 TCC 中的伤害性神经元活动[2]。 Animal Model: Sprague-Dawley rats, electricalstimulation was performed on the intact dura mater abovethe middle meningeal artery[2]. Dosage: 10 mg/kg Administration: i.v.; once Result: Induced an inhibition of stimulus-evoked nociceptive activity in the trigeminocervical com-plex (TCC).
References

[1]. Eloisa Rubio-Beltrán, et al. PACAP38 and PAC1 receptor blockade: a new target for headache? J Headache Pain. 2018 Aug 7;19(1):64.  

[2]. Hoffmann J, et al. PAC-1 receptor antibody modulates nociceptive trigeminal activity in rat. Cephalalgia. 2016;36(1S):141–141.

 Chemical & Physical Properties

No Any Chemical & Physical Properties
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