Molecular Nutrition & Food Research 2010-02-01

The Japanese toxicogenomics project: application of toxicogenomics.

Takeki Uehara, Atsushi Ono, Toshiyuki Maruyama, Ikuo Kato, Hiroshi Yamada, Yasuo Ohno, Tetsuro Urushidani

文献索引：Mol. Nutr. Food. Res. 54 , 218-27, (2010)

全文：HTML全文

摘要

Biotechnology advances have provided novel methods for the risk assessment of chemicals. The application of microarray technologies to toxicology, known as toxicogenomics, is becoming an accepted approach for identifying chemicals with potential safety problems. Gene expression profiling is expected to identify the mechanisms that underlie the potential toxicity of chemicals. This technology has also been applied to identify biomarkers of toxicity to predict potential hazardous chemicals. Ultimately, toxicogenomics is expected to aid in risk assessment. The following discussion explores potential applications and features of the Japanese Toxicogenomics Project.

相关化合物

  • 溴苯
  • 单宁酸
  • 萘普生
  • 利福平
  • 对乙酰氨基苯酚
  • 乙醇
  • L-乙硫胺酸
  • 舒林酸
  • 四氯化碳
  • 法莫替丁

相关文献：

Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).

2011-12-01

[J. Sci. Ind. Res. 65(10) , 808, (2006)]

The ionization mechanisms in direct and dopant-assisted atmospheric pressure photoionization and atmospheric pressure laser ionization.

2014-11-01

[J. Am. Soc. Mass Spectrom. 25(11) , 1870-81, (2014)]

Ion/molecule reactions for detecting ammonia using miniature cylindrical ion trap mass spectrometers.

2011-01-07

[Analyst 136(1) , 120-7, (2011)]

The contribution of bromobenzene to our current understanding of chemically-induced toxicities.

1988-01-01

[Life Sci. 42(13) , 1259-69, (1988)]

Synthesis of C-1 homologues of pancratistatin and their preliminary biological evaluation.

2011-08-15

[Bioorg. Med. Chem. Lett. 21(16) , 4750-2, (2011)]

更多文献...