Journal of Chromatography B 2015-12-01

Detection of ethanolamine altering in fetuses of pregnancy-associated hypertensive mice treated with vasodepressors by using UPLC and MALDI-TOF/MS.

Koichiro Kako, Ayumi Nakamura, Yusuke Nagashima, Junji Ishida, Akiyoshi Fukamizu

文献索引：J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 1006 , 93-8, (2015)

全文：HTML全文

摘要

Since serotonin, homocysteine and oxytocin are known to fluctuate during mammalian gestation, we screened amines altered in pregnant-associated hypertensive (PAH) mice by tagging their amino groups with 6-aminoquinoline carbamoyl (AQC) group in concert with ultra high-performance liquid chromatography (UPLC). Interestingly, a candidate amine significantly increased in PAH mice was recovered to the basal level, when treated with antihypertensive drugs. Mass spectrometric analyses indicated that the molecular mass of this amine was 61.2, which was identified as ethanolamine. Copyright © 2015 Elsevier B.V. All rights reserved.

相关化合物

  • 2,5-二羟基苯甲酸
  • 尿素
  • L-正缬氨酸

相关文献：

Structure and boosting activity of a starch-degrading lytic polysaccharide monooxygenase.

2015-01-01

[Nat. Commun. 6 , 5961, (2015)]

Antimicrobial activity of natural products from the flora of Northern Ontario, Canada.

2015-06-01

[Pharm. Biol. 53(6) , 800-6, (2015)]

Comparison of Mannose, Ethylene Glycol, and Methoxy-Terminated Diluents on Specificity and Selectivity of Electrochemical Peptide-Based Sensors.

2015-07-07

[Anal. Chem. 87 , 6966-73, (2015)]

Design and Evaluation of Tumor-Specific Dendrimer Epigenetic Therapeutics.

2015-06-01

[ChemistryOpen 4 , 335-41, (2015)]

Proteomics profiling of ethylene-induced tomato flower pedicel abscission.

2015-05-21

[J. Proteomics 121 , 67-87, (2015)]

更多文献...