Analyst (Cambridge UK) 2015-05-07

Tandem differential mobility spectrometry with ion dissociation in air at ambient pressure and temperature.

M R Menlyadiev, A Tarassov, A M Kielnecker, G A Eiceman

文献索引:Analyst 140(9) , 2995-3002, (2015)

全文:HTML全文

摘要

Proton-bound dimers were dissociated to protonated monomers in air at ambient pressure and temperature using electric fields of ultrahigh Field Asymmetric Ion Mobility Spectrometry (ultraFAIMS) with the onset of dissociation for ethyl acetate as 96 Td and for dimethyl methyl phosphonate as 170 Td. Ions then were measured by differential mobility spectrometry (DMS). Fragment ions were formed with propyl acetate at electric fields of 90 Td or greater. The dissociation in ultraFAIMS of ions, with compensation fields near zero, to form smaller ions with new compensation fields, provided a method to improve peak capacity in DMS without gas modifiers. These findings also lay the foundation for a triple stage DMS with a centre stage for ion dissociation or fragmentation.


相关化合物

  • 丙酮
  • 乙酸乙酯
  • 醋酸正丙酯
  • 甲基膦酸二甲酯

相关文献:

Aptamer-based polyvalent ligands for regulated cell attachment on the hydrogel surface.

2015-04-13

[Biomacromolecules 16(4) , 1382-9, (2015)]

Polymerization of affinity ligands on a surface for enhanced ligand display and cell binding.

2014-12-08

[Biomacromolecules 15(12) , 4561-9, (2014)]

Synergistic activity of tenofovir and nevirapine combinations released from polycaprolactone matrices for potential enhanced prevention of HIV infection through the vaginal route.

2014-10-01

[Eur. J. Pharm. Biopharm. 88(2) , 406-14, (2014)]

Use of an enzyme-assisted method to improve protein extraction from olive leaves.

2015-02-15

[Food Chem. 169 , 28-33, (2014)]

Molecular insights into shellac film coats from different aqueous shellac salt solutions and effect on disintegration of enteric-coated soft gelatin capsules.

2015-04-30

[Int. J. Pharm. 484(1-2) , 283-91, (2015)]

更多文献...