N-tritylprolinal: an efficient building block for the stereoselective synthesis of proline-derived amino alcohols.
Joseph Bejjani, Fabrice Chemla, Max Audouin
文献索引:J. Org. Chem. 68(25) , 9747-52, (2003)
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摘要
N-Tritylprolinal (prepared in four steps from l-proline) shows a very high Felkin diastereoselectivity in its reaction with various nucleophiles, leading to a straightforward and highly stereoselective access to syn-proline-derived amino alcohols.
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