Macromolecular Bioscience 2014-10-01

Zwitterionic red fluorescent polymeric nanoparticles for cell imaging.

Haiyin Li, Xiqi Zhang, Xiaoyong Zhang, Bin Yang, Yang Yang, Zengfang Huang, Yen Wei

文献索引：Macromol. Biosci. 14(10) , 1361-7, (2014)

全文：HTML全文

摘要

Phospholipid monomer and aggregation-induced emission (AIE) dye-based dimers are incorporated via reversible addition-fragmentation transfer polymerization to afford cross-linked zwitterionic fluorescent copolymers. Such copolymers are prone to self-assembly into fluorescent polymeric nanoparticles (FPNs) in physiological solution due to their amphiphilic nature. Characterization of these red FPNs by Fourier-transform infrared spectroscopy and X-ray photoelectron spectroscopy indicates the successful preparation of these zwitterionic copolymers. UV-visible absorption spectroscopy, fluorescence spectroscopy, transmission electron microscopy, and dynamic light scattering are performed to demonstrate the bright red fluorescence of the FPNs and their stable dispersibilities, even below the critical micelle concentration in physiological solution. Finally, studies of the biocompatibility and cell uptake behavior of the FPNs are conducted and show excellent biocompatibility for cell imaging application. © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

相关化合物

  • 2-甲基丙烯酰氧乙基...
  • 甲醇
  • 四丁基氢氧化铵
  • 四(三苯基膦)钯(0)
  • 对乙烯基苯基硼酸

相关文献：

Sorafenib resistance and JNK signaling in carcinoma during extracellular matrix stiffening.

2014-05-01

[Biomaterials 35(22) , 5749-59, (2014)]

Oncogenic Ras/ERK signaling activates CDCP1 to promote tumor invasion and metastasis.

2014-10-01

[Mol. Cancer Res. 12(10) , 1449-59, (2014)]

Real time visualization and characterization of platelet deposition under flow onto clinically relevant opaque surfaces.

2015-04-01

[J. Biomed. Mater. Res. A 103(4) , 1303-11, (2015)]

Long-term hip simulator testing of the artificial hip joint bearing surface grafted with biocompatible phospholipid polymer.

2014-03-01

[J. Orthop. Res. 32(3) , 369-76, (2014)]

Preparation of non-thrombogenic materials using 2-methacryloyloxyethyl phosphorylcholine.

2003-06-01

[Biomaterials 24(13) , 2431-5, (2003)]

更多文献...