FEBS Letters 2013-06-05

Mitochondrial dysfunction and nuclear-mitochondrial shuttling of TERT are involved in cell proliferation arrest induced by G-quadruplex ligands

Xin-Ying Zhuang, Yong-Gang Yao

文献索引：FEBS Lett. 587(11) , 1656-62, (2013)

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摘要

• DODC is more efficient in cell growth inhibition than TMPyP4. • Both DODC and TMPyP4 cause nuclear-mitochondrial shuttling of TERT. • Perturbation of mitochondrial function may account for the toxicity of DODC.

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