Phytotherapy Research 2013-02-01

Organ accumulation in mice after inhalation of single or mixed essential oil compounds.

Tadaaki Satou, Mizuho Takahashi, Hikaru Kasuya, Shio Murakami, Shinichiro Hayashi, Kiyomi Sadamoto, Kazuo Koike

文献索引：Phytother Res. 27(2) , 306-11, (2013)

全文：HTML全文

摘要

Essential oils are composed of multiple components. It is thought that the effect of essential oils is due to specific component ratios, which may differ from the original ratio when the essential oil is absorbed. However, very little detailed research exists in this area. We studied the distribution of essential oil components after inhalation of single and mixed components in mice. This research was done using four main components of Alpinia zerumbet (Pers.) B. L. Burtt. and R. M. Sm.: α-pinene, p-cymene, 1,8-cineole, and limonene. After inhalation of single or mixed components for 90 min, component levels in the brain and liver of mice were measured. The results indicated that the amount of α-pinene in the brain and liver was twofold greater after mixed-component inhalation than that after single-component inhalation. In a comparison of the components of the mixed inhalation, the ratio of α-pinene increased to about three times that of 1,8-cineole. It is thought that the absorption via the nasal mucus greatly influences this phenomenon. The results of this investigation of the bodily distribution of essential oil volatile components may provide clues for elucidating their action.Copyright © 2012 John Wiley & Sons, Ltd.

相关化合物

  • 4-异丙基甲苯
  • 桉叶油醇
  • α-蒎烯

相关文献：

Carvacrol and rosemary essential oil manifest cytotoxic, DNA-protective and pro-apoptotic effect having no effect on DNA repair.

2014-01-01

[Neoplasma 61(6) , 690-9, (2014)]

QSPR modeling of octanol/water partition coefficient for vitamins by optimal descriptors calculated with SMILES.

2008-04-01

[Eur. J. Med. Chem. 43 , 714-40, (2008)]

Identification of odorants in frankincense (Boswellia sacra Flueck.) by aroma extract dilution analysis and two-dimensional gas chromatography-mass spectrometry/olfactometry.

2015-01-01

[Phytochemistry 109 , 66-75, (2014)]

Anaerobic activation of p-cymene in denitrifying betaproteobacteria: methyl group hydroxylation versus addition to fumarate.

2014-12-01

[Appl. Environ. Microbiol. 80(24) , 7592-603, (2014)]

Phytochemical analysis and in vitro biological activity of three Hypericum species from the Canary Islands (Hypericum reflexum, Hypericum canariense and Hypericum grandifolium).

2015-01-01

[Fitoterapia 100 , 95-109, (2015)]

更多文献...