Journal of Peptide Research 2004-03-01

Synthesis of 9-membered dilactams derived from 1,3-diaminopropionic and glutamic acids.

A N Chulin, I L Rodionov, V T Ivanov

文献索引:J. Pept. Res. 63(3) , 235-40, (2004)

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摘要

Previously unknown 9-membered bridged dipeptides derived from l or d isomers of 1,3-diaminopropionic acids and l-glutamic acid were synthesized using aminoacyl incorporation reaction. Key intermediates containing internal pyroglutamyl moiety were prepared via side chain to backbone cyclization of related protected dipeptide derivatives of glutamic acid.


相关化合物

  • DL-2,3-二氨基丙酸...
  • L(+)-2,3-二氨基丙...

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