Unsaturated free fatty acids: a potential biomarker panel for early detection of gastric cancer.
Yaping Zhang, Ling Qiu, Yanmin Wang, Chengyan He, Xuzhen Qin, Yujie Liu, Zhili Li
文献索引:Biomarkers 19(8) , 667-73, (2014)
全文:HTML全文
摘要
Changes in the levels of free fatty acids (FFAs) are closely associated with physiological status. Serum levels of C16:1, C18:3, C18:2, C18:1, C20:4, and C22:6 in 164 gastric cancer (GC) patients and 111 benign gastric disease (BGD) patients were significantly decreased compared with 252 healthy controls. Receiver operating characteristic analysis showed that the biomarker panel including C16:1, C18:3, C18:2, C20:4, and C22:6 presents a high diagnostic ability to differentiate early-stage GC patients from healthy controls plus BGD patients, with a sensitivity of 80.6% and a specificity of 72.7%.
相关化合物
相关文献:
2015-03-15
[Cancer Res. 75(6) , 1102-12, (2015)]
2015-04-13
[Biomacromolecules 16(4) , 1382-9, (2015)]
2015-04-22
[J. Ethnopharmacol. 164 , 265-72, (2015)]
2015-01-01
[Bioresour. Technol. 176 , 156-62, (2014)]
2014-12-08
[Biomacromolecules 15(12) , 4561-9, (2014)]