Suzuki-Miyaura cross-coupling of potassium dioxolanylethyltrifluoroborate and aryl/heteroaryl chlorides.
Nicolas Fleury-Brégeot, Daniel Oehlrich, Frederik Rombouts, Gary A Molander
文献索引：Org. Lett. 15(7) , 1536-9, (2013)
全文：HTML全文
摘要
A robust and efficient protocol for the introduction of the dioxolanylethyl moiety onto various aryl and heteroaryl halides has been developed, providing cross-coupling yields up to 93%. Copper-catalyzed borylation of 2-(2-bromoethyl)-1,3-dioxolane with bis(pinacolato)diboron followed by treatment with potassium bifluoride provides the key organotrifluoroborate reagent.
相关化合物
相关文献：
1999-07-01
[Chem. Phys. Lipids 100(1-2) , 33-40, (1999)]
[Tetrahedron Lett. 34 , 6411, (1993)]
[Tetrahedron Lett. 34 , 7705, (1993)]
[J. Chem. Soc. Perkin Trans. I , 15, (1994)]
[J. Chem. Soc. Perkin Trans. I , 681, (1993)]