Molecules 2015-01-01

Amination of Aryl Halides and Esters Using Intensified Continuous Flow Processing.

Thomas M Kohl, Christian H Hornung, John Tsanaktsidis

文献索引：Molecules 20 , 17860-71, (2015)

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摘要

Significant process intensification of the amination reactions of aryl halides and esters has been demonstrated using continuous flow processing. Using this technology traditionally difficult amination reactions have been performed safely at elevated temperatures. These reactions were successfully conducted on laboratory scale coil reactor modules with 1 mm internal diameter (ID) and on a preparatory scale tubular reactor with 6 mm ID containing static mixers.

相关化合物

  • 异丙醇
  • 甲醇
  • 氨基甲烷
  • 二氯甲烷
  • 二甲基亚砜
  • 4-溴吡啶盐酸盐
  • 氨
  • 4-氯-3-硝基苯磺酸...
  • 3-巯基丙酸甲酯
  • AMMONIA (14N)

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