PLoS ONE 2008-01-01

The mych gene is required for neural crest survival during zebrafish development.

Sung-Kook Hong, Michael Tsang, Igor B Dawid

文献索引：PLoS ONE 3(4) , e2029, (2008)

全文：HTML全文

摘要

Among Myc family genes, c-Myc is known to have a role in neural crest specification in Xenopus and in craniofacial development in the mouse. There is no information on the function of other Myc genes in neural crest development, or about any developmental role of zebrafish Myc genes.We isolated the zebrafish mych (myc homologue) gene. Knockdown of mych leads to severe defects in craniofacial development and in certain other tissues including the eye. These phenotypes appear to be caused by cell death in the neural crest and in the eye field in the anterior brain.Mych is a novel factor required for neural crest cell survival in zebrafish.

相关化合物

  • 甲基绿
  • 阿尔新蓝8GX

相关文献：

Developmental Expression and Glucocorticoid Control of the Leptin Receptor in Fetal Ovine Lung.

2015-01-01

[PLoS ONE 10 , e0136115, (2015)]

Design, Preparation, and Characterization of Zn and Cu Metallopeptides Based On Tetradentate Aminopyridine Ligands Showing Enhanced DNA Cleavage Activity.

2015-11-16

[Inorg. Chem. 54 , 10542-58, (2015)]

Luminescent europium and terbium complexes of dipyridoquinoxaline and dipyridophenazine ligands as photosensitizing antennae: structures and biological perspectives.

2015-12-14

[Dalton Trans. 44 , 19844-55, (2015)]

Modulation of Fas-Fas Ligand Interaction Rehabilitates Hypoxia-Induced Apoptosis of Mesenchymal Stem Cells in Ischemic Myocardium Niche.

2015-01-01

[Cell. Transplant. 24 , 1329-41, (2015)]

Bone status of acetylcholinesterase-knockout mice.

2015-11-01

[Int. Immunopharmacol. 29 , 222-30, (2015)]

更多文献...