Bioorganic & Medicinal Chemistry Letters 2008-01-01

Eco-friendly and efficient one-pot synthesis of alkyl- or aryl-14H-dibenzo[a,j]xanthenes in water.

Minoo Dabiri, Mostafa Baghbanzadeh, Maryam Shakouri Nikcheh, Elham Arzroomchilar

文献索引:Bioorg. Med. Chem. Lett. 18(1) , 436-8, (2008)

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摘要

Alkyl- or aryl-14H-dibenzo[a,j]xanthene derivatives are synthesized efficiently by the reaction of beta-naphthol and aliphatic and aromatic aldehydes in the presence of KAl(SO4)2 x 12 H2O (alum) under aqueous condition at 100 degrees C. Different types of aromatic and aliphatic aldehydes are used in the reaction and in all cases the products synthesized successfully. Several solvents were examined for this reaction; however, in terms of reaction yield and time, water was found to be the optimum solvent.


相关化合物

  • 4-氯苯甲酰肼

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