Natural product communications 2015-06-01

Polyurethane Microstructures--a Good or Bad in vitro Partner for the Isoflavone Genistein?

Corina Danciu, Florin Borcan, Codruta Soica, Istvan Zupko, Erzsébet Csányi, Rita Ambrus, Delia Muntean, Camelia Sass, Diana Antal, Claudia Toma, Cristina Dehelean

文献索引：Nat. Prod. Commun. 10 , 951-4, (2015)

全文：HTML全文

摘要

In recent years polyurethane microstructures (PM) have gained increasing attention in the pharmaceutical field due to the importance of their practical application. Since finding that such a formulation with genistein could improve its applications, we have conducted a preliminary study regarding the in vitro antiproliferative (MCF7, MDA-MB-231 and T47D) and antimicrobial (Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa, Salmonella enteritidis (D), Bacillus subtilis, B. cereus, and Candida albicans) activity in order to test whether polyurethane micro structuresre present a good option for further modulation of genistein's bioavailability. It was concluded that the polyurethane micro structures are a bad in vitro partner for the isoflavone genistein.

相关化合物

  • 异丙醇
  • L-赖氨酸盐酸盐
  • 乙二醇
  • 染料木素
  • 异佛尔酮二异氰酸酯

相关文献：

Genome-wide shRNA screening identifies host factors involved in early endocytic events for HIV-1-induced CD4 down-regulation.

2014-01-01

[Retrovirology 11 , 118, (2015)]

Comparative in vitro study on magnetic iron oxide nanoparticles for MRI tracking of adipose tissue-derived progenitor cells.

2014-01-01

[PLoS ONE 9(9) , e108055, (2014)]

Comparison of the antifungal efficacy of terbinafine hydrochloride and ciclopirox olamine containing formulations against the dermatophyte Trichophyton rubrum in an infected nail plate model.

2014-07-07

[Mol. Pharm. 11(7) , 1991-6, (2014)]

Novel in silico-designed estradiol analogues are cytotoxic to a multidrug-resistant cell line at nanomolar concentrations.

2015-02-01

[Cancer Chemother. Pharmacol. 75(2) , 431-7, (2015)]

Use of an enzyme-assisted method to improve protein extraction from olive leaves.

2015-02-15

[Food Chem. 169 , 28-33, (2014)]

更多文献...