Advanced Healthcare Materials 2015-07-15

S-Nitrosated Polypropylene Sulfide Nanoparticles for Thiol-Dependent Transnitrosation and Toxicity Against Adult Female Filarial Worms.

Alex Schudel, Timothy Kassis, J Brandon Dixon, Susan N Thomas

文献索引：Adv. Healthc. Mater. 4(10) , 1484-90, 1423, (2015)

全文：HTML全文

摘要

A synthetic polymer nanoparticle formulation utilizing the physiological nitrosothiol chemistry for nitric oxide delivery is shown. Toxicity of S-nitroso nanoparticles against adult female Brugia malayi worms, which are responsible for lymphatic filariasis, is dependent on nitric oxide release through transnitrosation as S-nitrosocysteine, a potent endogenous nitric oxide donor. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

相关化合物

  • 氨基磺酸铵
  • 氯化汞
  • 磺胺
  • 盐酸萘乙二胺
  • 甲醇钠
  • 醋酸氢化可的松
  • 泊洛沙姆188
  • 硫化丙烯

相关文献：

Cloning, characterization and sulfonamide inhibition studies of an α-carbonic anhydrase from the living fossil sponge Astrosclera willeyana.

2012-02-15

[Bioorg. Med. Chem. 20 , 1403-10, (2012)]

Nitric Oxide Down-Regulates Topoisomerase I and Induces Camptothecin Resistance in Human Breast MCF-7 Tumor Cells.

2015-01-01

[PLoS ONE 10 , e0141897, (2015)]

Correlation of oxidant status with oxidative tissue damage in patients with rheumatoid arthritis.

2014-11-01

[Clin. Rheumatol. 33(11) , 1557-64, (2014)]

Ethylenediammonium dication: H-bonded complexes with terephthalate, chloroacetate, phosphite, selenite and sulfamate anions. Detailed vibrational spectroscopic and theoretical studies of ethylenediammonium terephthalate.

2012-12-01

[Spectrochim. Acta. A. Mol. Biomol. Spectrosc. 99 , 223-33, (2012)]

Modular functionalization of allenes to aminated stereotriads.

2012-07-04

[J. Am. Chem. Soc. 134(26) , 10807-10, (2012)]

更多文献...