Organic Letters 2013-03-15

Phase-transfer-catalyzed asymmetric conjugate cyanation of alkylidenemalonates with KCN in the presence of a Brønsted acid additive.

Yan Liu, Seiji Shirakawa, Keiji Maruoka

文献索引：Org. Lett. 15(6) , 1230-3, (2013)

全文：HTML全文

摘要

Highly enantioselective conjugate cyanation of alkylidenemalonates with KCN was achieved under mild phase-transfer conditions with a bifunctional phase-transfer catalyst. The effect of Brønsted acid additives was examined based on the hypothetical catalytic cycle, and the Brønsted acid additive was found to be essential to promote the conjugate cyanation efficiently.

相关化合物

  • 溴化铵
  • potassium,azanylid...
  • 氰化钾

相关文献：

Mesoporous silica coated gold nanorods loaded doxorubicin for combined chemo-photothermal therapy.

2014-08-15

[Int. J. Pharm. 470(1-2) , 1-7, (2014)]

Dispersive micro-solid-phase extraction of benzodiazepines from biological fluids based on polyaniline/magnetic nanoparticles composite.

2014-09-24

[Anal. Chim. Acta 844 , 80-9, (2014)]

Lipocalin-2 promotes m1 macrophages polarization in a mouse cardiac ischaemia-reperfusion injury model.

2015-01-01

[Scand. J. Immunol. 81(1) , 31-8, (2014)]

5-Aminosalicylic acid attenuates allergen-induced airway inflammation and oxidative stress in asthma.

2014-12-01

[Pulm. Pharmacol. Ther. 29(2) , 209-16, (2014)]

Cationic lipid-assisted polymeric nanoparticle mediated GATA2 siRNA delivery for synthetic lethal therapy of KRAS mutant non-small-cell lung carcinoma.

2014-08-04

[Mol. Pharm. 11(8) , 2612-22, (2014)]

更多文献...