Efficient Cu-catalyzed base-free C-S coupling under conventional and microwave heating. A simple access to S-heterocycles and sulfides.
Silvia M Soria-Castro, Alicia B Peñéñory
文献索引:Beilstein J. Org. Chem. 9 , 467-75, (2013)
全文:HTML全文
摘要
S-aryl thioacetates can be prepared by reaction of inexpensive potassium thioacetate with both electron-rich and electron-poor aryl iodides under a base-free copper/ligand catalytic system. CuI as copper source affords S-aryl thioacetates in good to excellent yields, by using 1,10-phenanthroline as a ligand in toluene at 100 °C after 24 h. Under microwave irradiation the time was drastically reduced to 2 h. Both procedures are simple and involve a low-cost catalytic system. This methodology was also applied to the "one-pot" synthesis of target heterocycles, such as 3H-benzo[c][1,2]dithiol-3-one and 2-methylbenzothiazole, alkyl aryl sulfides, diaryl disulfides and asymmetric diaryl sulfides in good yields.
相关化合物
相关文献:
2015-04-01
[Environ. Sci. Pollut. Res. Int. 22(8) , 5842-9, (2015)]
2010-01-01
[J. Chromatogr. A. 1338 , 164-73, (2014)]
2015-11-09
[Chemistry 21 , 16623-30, (2015)]
2015-07-01
[Colloid Polym. Sci. 293 , 1865-1876, (2015)]
[Zh. Org. Khim. 28 , 2159, (1992)]