Organic Letters
2006-11-09
Copper-catalyzed asymmetric conjugate addition of diethylzinc to alpha,beta-unsaturated imines derived from alpha-aminoacids. Enantioselective synthesis of gamma-substituted alpha-dehydroaminoesters.
Francisco Palacios, Javier Vicario
文献索引:Org. Lett. 8 , 5405, (2006)
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摘要
[Structure: see text] A highly enantioselective synthesis of alpha-dehydroaminoacids with a stereogenic center in the gamma position through copper-catalyzed asymmetric conjugate addition of diethylzinc to alpha,beta-unsaturated imines using a TADDOL-derived phosphoramidite complex is reported.
相关化合物
相关文献:
[Tetrahedron Lett. 48 , 3305, (2007)]