Assessment of a twice dosing regimen both before and after partial hepatectomy in the rat liver micronucleus test
Satoru Itoh, Miyuki Igarashi, Mayumi Nagata, Chiharu Hattori
文献索引:Mutat. Res. Genet. Toxicol. Environ. Mutagen. 782 , 18-23, (2015)
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摘要
• Effectiveness of twice dosing regimen was evaluated in the rat liver MN test. • Results from twice dosing regimen are similar to those from single dosing regimens. • Twice dosing regimen could detect clastogenic and aneugenic activity simultaneously.
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