Plant Molecular Biology 2013-04-01

The Arabidopsis thaliana ortholog of a purported maize cholinesterase gene encodes a GDSL-lipase.

Mrinalini Muralidharan, Kristina Buss, Katherine E Larrimore, Nicholas A Segerson, Latha Kannan, Tsafrir S Mor

文献索引：Plant Mol. Biol. 81(6) , 565-76, (2013)

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摘要

Acetylcholinesterase is an enzyme that is intimately associated with regulation of synaptic transmission in the cholinergic nervous system and in neuromuscular junctions of animals. However the presence of cholinesterase activity has been described also in non-metazoan organisms such as slime molds, fungi and plants. More recently, a gene purportedly encoding for acetylcholinesterase was cloned from maize. We have cloned the Arabidopsis thaliana homolog of the Zea mays gene, At3g26430, and studied its biochemical properties. Our results indicate that the protein encoded by the gene exhibited lipase activity with preference to long chain substrates but did not hydrolyze choline esters. The At3g26430 protein belongs to the SGNH clan of serine hydrolases, and more specifically to the GDS(L) lipase family.

相关化合物

  • 脂肪酶
  • 丁酰胆碱酯酶 来源...
  • 脂肪酶来自绿脓杆菌

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