Nucleosides, Nucleotides & Nucleic Acids 2008-02-01

"One-pot" syntheses of malondialdehyde adducts of nucleosides.

Jozsef Szekely, Hao Wang, Katherine M Peplowski, Charles G Knutson, Lawrence J Marnett, Carmelo J Rizzo

文献索引：Nucleosides Nucleotides Nucleic Acids 27(2) , 103-9, (2008)

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摘要

Short, "one-pot" syntheses of malondialdehyde adducts of deoxyguanosine, deoxyadenosine, and deoxycytidine are described. These syntheses proceed in improved yield and easier purification than previous syntheses and are well suited for the preparation of isotopically labeled nucleoside adducts for biomarker and metabolic studies.

相关化合物

  • 顺-3-溴丙烯酸乙酯

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