Journal of Antibiotics 1993-12-01

Synthesis of 3-episiastatin B analogues having anti-influenza virus activity.

Y Nishimura, Y Umezawa, S Kondo, T Takeuchi, K Mori, I Kijima-Suda, K Tomita, K Sugawara, K Nakamura

文献索引：J. Antibiot. 46(12) , 1883-9, (1993)

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摘要

Two epimers of siastatin B, 3-episiastatin B (3) and 3,4-diepisiastatin B (4), were obtained by the chemical modification of siastatin B. Compound 3 showed marked inhibitory activity against influenza virus neuraminidases and significant inhibition of influenza virus infection in vitro.

相关化合物

  • Siastatin B micro...

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