Organic Letters
2002-04-04
Enantioselective aziridination of alkenes with N-aminophthalimide in the presence of lead tetraacetate-mediated chiral ligand.
Kung-Shou Yang, Kwunmin Chen
文献索引:Org. Lett. 4(7) , 1107-9, (2002)
全文:HTML全文
摘要
[reaction: see text] Reaction of various N-enoyl oxazolidinones 5a-f with N-aminophthalimide and lead tetraacetate in the presence of camphor-derived chiral ligands provides the desired N-phthalimidoaziridines 6a-f in good to high enantiomeric excess (67-95% ee) at 0 degrees C within 15 min. The absolute stereochemistry of the corresponding aziridine derivatives was established by chemical correlations.
相关化合物
相关文献:
[J. Chem. Soc. Chem. Commun. , 1074, (1993)]