Organic Letters 2007-05-10

Catalytic asymmetric formation of beta-sultams.

Marian Zajac, René Peters

文献索引：Org. Lett. 9 , 2007, (2007)

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摘要

beta-Sultams, highly strained sulfonyl analogues of beta-lactams, were prepared enantio- and diastereoselectively by tertiary amine catalyzed [2 + 2] cycloaddition reactions. The title compounds are practical precursors of highly enantioenriched biologically interesting beta-aminosulfonyl derivatives.

相关化合物

  • 3-氯丙烷磺酰氯
  • 磺酰氯

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