Bioconjugate Chemistry 1997-01-01

Preparation and properties of oligodeoxynucleotides containing 5-iodouracil and 5-bromo- and 5-iodocytosine.

E Ferrer, M Wiersma, B Kazimierczak, C W Müller, R Eritja

文献索引：Bioconjug. Chem. 8(5) , 757-61, (1997)

全文：HTML全文

摘要

The behavior of oligonucleotides containing 5-iodouracil, 5-bromocytidine, and 5-iodocytidine in concentrated ammonia is described. 5-Aminouracil and 5-aminocytidine are obtained as side products when deprotection is performed at 60 degrees C. Small amounts, if any, of side products are obtained when ammonia deprotection is performed at room temperature. The base-pairing properties of these 5-halopyrimidines including triple helix are described.

相关化合物

  • 5-溴胞嘧啶
  • 5-碘尿嘧啶
  • 5-碘胞核嘧啶

相关文献：

Structure-activity relationships of beta-D-(2S,5R)- and alpha-D-(2S,5S)-1,3-oxathiolanyl nucleosides as potential anti-HIV agents.

1993-09-03

[J. Med. Chem. 36(18) , 2627-38, (1993)]

Formation of intrastrand cross-link products between cytosine and adenine from UV irradiation of d((Br)CA) and duplex DNA containing a 5-bromocytosine.

2005-10-12

[J. Am. Chem. Soc. 127(40) , 13969-77, (2005)]

Lifetime regulation of the charge-separated state in DNA by modulating the oxidation potential of guanine in DNA through hydrogen bonding.

2004-10-13

[J. Am. Chem. Soc. 126(40) , 12843-6, (2004)]

Crystal structure of a DNA Holliday junction.

1999-10-01

[Nat. Struct. Biol. 6(10) , 913-7, (1999)]

Epigenetics of chronic rhinosinusitis and the role of the eosinophil.

2012-01-01

[Int. Forum Allergy Rhinol. 2(1) , 80-4, (2012)]

更多文献...