Chemical Communications 2005-02-07

gem-Difluorination of 2,2-diaryl-1,3-dithiolanes by Selectfluor and pyridinium polyhydrogen fluoride.

V Prakash Reddy, Ramesh Alleti, Meher K Perambuduru, Urs Welz-Biermann, Herwig Buchholz, G K Surya Prakash

文献索引：Chem. Commun. (Camb.) , 654, (2005)

全文：HTML全文

摘要

2,2-diaryl-1,3-dithiolanes, readily obtainable from diaryl ketones, were transformed into the corresponding gem-difluoro compounds using a novel reagent combination involving Selectfluor and pyridinium polyhydrogen fluoride (PPHF) under mild conditions in moderate to good yields.

相关化合物

  • 1,3-二硫代坊
  • 吡啶氢氟酸盐

相关文献：

Cationic cyclization of 2-alkenyl-1,3-dithiolanes: diastereoselective synthesis of trans-decalins.

2011-05-06

[J. Org. Chem. 76(9) , 3274-85, (2011)]

Alpha-keto amide peptides: a synthetic strategy to resin-bound peptide isosteres for protease inhibitor screening on solid support.

2004-01-01

[J. Comb. Chem. 6(2) , 181-95, (2004)]

Diastereoselective formal total synthesis of (+/-)-triptolide via a novel cationic cyclization of 2-alkenyl-1,3-dithiolane.

2010-08-21

[Chem. Commun. (Camb.) 46(31) , 5778-80, (2010)]

Dithiolane analogs of lignans inhibit interferon-gamma and lipopolysaccharide-induced nitric oxide production in macrophages.

2000-10-01

[Acta Pharmacol. Sin. 21(10) , 897-904, (2000)]

Synthesis, DNA intercalation and 3D QSAR analysis of cis-2,4,5-trisubstituted-1,3-dithiolanes as a novel class of antitumor agents.

2009-08-15

[Bioorg. Med. Chem. 17 , 6085-95, (2009)]

更多文献...