Organic Letters 2014-07-03

Direct synthesis of pentafluoroethyl copper from pentafluoropropionate as an economical C2F5 source: application to pentafluoroethylation of arylboronic acids and aryl bromides.

Hiroki Serizawa, Kohsuke Aikawa, Koichi Mikami

文献索引：Org. Lett. 16(13) , 3456-9, (2014)

全文：HTML全文

摘要

The direct synthesis of pentafluoroethyl copper (CuC2F5) from a cuprate reagent and ethyl pentafluoropropionate as one of the most economical and useful pentafluoroethyl sources was accomplished. The advantages of this method are; all the reagents employed are low-cost and operationally simple, and the CuC2F5 reagent is prepared in virtually quantitative yield. Furthermore, the CuC2F5 reagent prepared was successfully applied to two types of pentafluoroethylations with arylboronic acids and aryl bromides to provide the pentafluoroethylated aromatic products in good-to-excellent yields, including large scale operations.

相关化合物

  • 铜粉
  • 五氟丙酸乙酯

相关文献：

Non-stabilized nucleophiles in Cu-catalysed dynamic kinetic asymmetric allylic alkylation.

2015-01-15

[Nature 517(7534) , 351-5, (2015)]

ROI-SCAVENGING ENZYME ACTIVITIES AS TOXICITY BIOMARKERS IN THREE SPECIES OF MARINE MICROALGAE EXPOSED TO MODEL CONTAMINANTS (COPPER, IRGAROL AND ATRAZINE)

1978-01-01

[Ecotoxicol. Environ. Saf. 104 , 294-301, (2014)]

Influence of the selective EDTA derivative phenyldiaminetetraacetic acid on the speciation and extraction of heavy metals from a contaminated soil.

2014-08-01

[Chemosphere 109 , 1-6, (2014)]

Synergistic effects of TiO2 and Cu2O in UV/TiO2/zeolite-based systems on photodegradation of bisphenol A.

2014-08-01

[Environ. Technol. 35(13-16) , 1851-7, (2014)]

Physiological responses of biomass allocation, root architecture, and invertase activity to copper stress in young seedlings from two populations of Kummerowia stipulacea (maxim.) Makino.

2014-05-01

[Ecotoxicol. Environ. Saf. 104 , 278-84, (2014)]

更多文献...