Synthesis of carbon-11 labeled sulfonanilide analogues as new potential PET agents for imaging of aromatase in breast cancer.
Min Wang, Gabrielle Lacy, Mingzhang Gao, Kathy D Miller, George W Sledge, Qi-Huang Zheng
文献索引：Bioorg. Med. Chem. Lett. 17(2) , 332-6, (2007)
全文：HTML全文
摘要
Aromatase is a particularly good target in the treatment of estrogen receptor positive breast cancer. Novel carbon-11 labeled sulfonanilide analogues, N-[11C]methyl-N-(2-alkyloxy-4-nitrophenyl)-methanesulfonamides ([11C]3a-f, alkyl=propyl, isopropyl, 1-ethyl-propyl, cyclopentyl, cyclohexyl, and cyclohexylethyl), were designed and synthesized as potential PET agents for imaging of aromatase in breast cancer.
相关化合物
相关文献：
2012-01-21
[Chem. Soc. Rev. 41(2) , 597-607, (2012)]
Isomerization of alkyl branched alkynoic acids. Abrams S R.
[Can. J. Chem. 64(3) , 457-463, (1986)]