Bioorganic & Medicinal Chemistry Letters 2005-11-15

Insecticidal anthranilic diamides: a new class of potent ryanodine receptor activators.

George P Lahm, Thomas P Selby, John H Freudenberger, Thomas M Stevenson, Brian J Myers, Gilles Seburyamo, Ben K Smith, Lindsey Flexner, Christopher E Clark, Daniel Cordova

文献索引：Bioorg. Med. Chem. Lett. 15 , 4898-906, (2005)

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摘要

A novel class of anthranilic diamides has been discovered with exceptional insecticidal activity on a range of Lepidoptera. These compounds have been found to exhibit their action by release of intracellular Ca2+ stores mediated by the ryanodine receptor. The discovery, synthesis, structure-activity, and biological results are presented.

相关化合物

  • 氯氰菊酯
  • 右旋反式苯醚菊酯
  • 3-三氟甲基吡唑

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