Journal of Lipid Research 1974-11-01

Subcellular localization of hexadecanedioic acid activation in human liver.

J E Pettersen, M Aas

文献索引：J. Lipid Res. 15(6) , 551-6, (1974)

全文：HTML全文

摘要

The activation of hexadecanedioic acid has been studied in subcellular fractions of human liver. The activation capacity in a total homogenate of human liver was found to be 0.5 micro mole/min/g wet wt of tissue, about 10% of that for palmitic acid. Hexadecanedioic acid was activated by the mitochondrial and microsomal fractions. The mitochondrial enzyme is probably localized outside the inner mitochondrial compartment. The subcellular distribution of the hexadecanedioic acid activation was almost identical with the distribution of palmitic acid activation. Hexadecanedioic and palmitic acids seemed to compete for the same enzyme.

相关化合物

  • 十六烷二酸

相关文献：

Feasibility of detecting prostate cancer by ultraperformance liquid chromatography-mass spectrometry serum metabolomics.

2014-07-03

[J. Proteome Res. 13(7) , 3444-54, (2014)]

Alkylthioacetic acids (3-thia fatty acids) as non-beta-oxidizable fatty acid analogues: a new group of hypolipidemic drugs. III. Dissociation of cholesterol- and triglyceride-lowering effects and the induction of peroxisomal beta-oxidation.

1989-11-01

[J. Lipid Res. 30(11) , 1711-8, (1989)]

Alkyl and carboxylalkyl esters of 4'-demethyl-4-deoxypodophyllotoxin: synthesis, cytotoxic, and antitumor activity.

2004-02-01

[Eur. J. Med. Chem. 39(2) , 189-93, (2004)]

Cytochrome P450BM-3 (CYP102): regiospecificity of oxidation of omega-unsaturated fatty acids and mechanism-based inactivation.

1993-12-14

[Biochemistry 32(49) , 13732-41, (1993)]

Hexadecanedionic acid-sepharose 4B: A new tool for preparation of albumin-depleted plasma.

2006-12-01

[J. Proteome Res. 5(12) , 3453-8, (2006)]

更多文献...