Organic Letters 2009-02-19

A general method for the synthesis of unsymmetrically substituted ureas via palladium-catalyzed amidation.

Brian J Kotecki, Dilinie P Fernando, Anthony R Haight, Kirill A Lukin

文献索引：Org. Lett. 11 , 947, (2009)

全文：HTML全文

摘要

A general and practical method for the preparation of unsymmetrically substituted ureas has been developed utilizing palladium-catalyzed amidation. Both aryl bromides and chlorides, as well as heteroaryl chlorides, have been coupled to aryl, benzyl, and aliphatic ureas by using a novel nonproprietary bipyrazole ligand (bippyphos).

相关化合物

  • 5-二叔丁基膦-1',3'...

相关文献：

A general and efficient catalyst for palladium-catalyzed C-O coupling reactions of aryl halides with primary alcohols.

2010-08-25

[J. Am. Chem. Soc. 132 , 11592, (2010)]

Palladium-catalyzed coupling of hydroxylamines with aryl bromides, chlorides, and iodides.

2009-01-01

[Org. Lett. 11 , 233, (2009)]

[Tetrahedron Lett. 47 , 3727, (2006)]

更多文献...