Acta poloniae pharmaceutica 2011-01-01

Spectrophotometric determination of bacitracin in bulk drug as dabsyl derivative in a range of visible light.

Jan Krzek, Joanna Piotrowska

文献索引：Acta Pol. Pharm. 68(6) , 853-8, (2011)

全文：HTML全文

摘要

A fast spectrophotometric method has been developed for bacitracin identification and determination after condensation reaction with dabsyl chloride. In addition, determination of dye stability of sulfonamide derivative and identification of the molar ratio of reagents was done at various time-points. The developed method has a good linearity with very broad spectrum, correlation coefficient of r = 0.9972, good precision (RSD = 1.54 +/- 0.11%), and recovery at three different levels of concentration was found between 98.33% and 103.47%. Usefulness of the method was demonstrated by positive results obtained during determination of bacitracin concentration in bulk drug.

相关化合物

  • 二甲基黄
  • 4-二甲胺基苯基偶氮...

相关文献：

Stabilization of resveratrol in blood circulation by conjugation to mPEG and mPEG-PLA polymers: investigation of conjugate linker and polymer composition on stability, metabolism, antioxidant activity and pharmacokinetic profile.

2015-01-01

[PLoS ONE 10(3) , e0118824, (2015)]

Membrane topology of the colicin E1 channel using genetically encoded fluorescence.

2011-06-07

[Biochemistry 50(22) , 4830-42, (2011)]

Edible oil adulterants, argemone oil and butter yellow, as aetiological factors for gall bladder cancer.

2012-09-01

[Eur. J. Cancer 48(13) , 2075-85, (2012)]

Lysine-directed staining of proteins for MS-based analyses.

2013-02-01

[Electrophoresis 34(3) , 401-4, (2013)]

DFT study of the interaction between the conjugated fluorescein and dabcyl system, using fluorescene quenching method.

2012-09-01

[J. Mol. Model. 18(9) , 4113-20, (2012)]

更多文献...