Chemoselective nitration of aromatic sulfonamides with tert-butyl nitrite.
Brenden Kilpatrick, Markus Heller, Steve Arns
文献索引:Chem. Commun. (Camb.) 49(5) , 514-6, (2013)
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摘要
A methodology for the efficient conversion of aromatic sulfonamides into their mono-nitro derivatives using tert-butyl nitrite is reported. The reaction exhibits a high degree of chemoselectivity for sulfonamide functionalized aryl systems, even in the presence of other sensitive or potentially reactive functionalities.
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